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Figure 6 | Journal of Biomedical Science

Figure 6

From: Up-regulation of S100A16 expression promotes epithelial-mesenchymal transition via Notch1 pathway in breast cancer

Figure 6

S100A16 activated Notch1 transcriptional activity. Dual luciferase reporter assay showed that transcriptional activities were increased in four transfected plasmids in S100A16-transduced MCF-7 cells (Bars, mean ± SD, P < 0.05). However, the region from −1496 to +76 had the strongest promoter activity. It seemed that the region from −1496 to −998 was the core part accounting for increasing promoter activity.

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