Figure 2From: KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity Effect of KUD773 on cell cycle progression and apoptosis. PC-3 cells were treated without or with KUD773 (3 μM) for the indicated times. Then, the cells were fixed and stained with PI to analyze DNA content by flow cytometric analysis. Data are expressed as mean ± SEM of three determinations. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with the zero time control.Back to article page