Figure 4
From: EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex
Cell Uptake of the PEI nanocomplex by MCF-7 and WERI-Rb1 cells. The fabricated PEI complexes and free aptamer were added to MCF-7 cells (upper panel A-E), WERI-Rb1 cells (lower panel A-E) and incubated for their uptake at 37°C for 4 h followed DAPI counterstaining and microscopic evaluation. Images were taken at 40× using AxioObserver fluorescent microscope. Legend on the top of phase image represents the aptamer or nanocomplex added to the respective panels.