Table 2 The comparisons of the genomic difference in the combinations of ITGA5 -1160 T-carrier, ITGB1 -1949 A-carrier, ITGB1 +31804 C-carrier, IL10 -592 AA and COX-2 -1195 G-carrier between the children of gastric cancer patients and the duodenal ulcer controls

ITGA5 -1160

(N = 189)

(N = 134)

 T-carrier

3R:2R:1R:0R

126(67): 49(26): 12(6): 2(1)

63(47): 48(36): 18(13): 5(4)

0.002

ITGB1 -1949

 A-carrier

3R

126 (67)

63 (47)

0.225

0.050

5 (0.9 - 26.5)

ITGB1 +31804

2R

49 (26)

48 (36)

0.539

0.514

2.6 (0.5 - 13.8)

 C-carrier

1R

12 (6)

18 (23)

0.575

0.756

1.7 (0.3 - 10.0)

0R

2 (21)

5 (4)

1

COX-2 -1195

(N = 188)

(N = 125)

 G-carrier

2R: 1R: 0R

80 (43): 93 (49): 15 (8)

31 (25): 75 (60): 19 (15)

0.013

With or without

IL-10 -592 AA

2R

80 (43)

31 (25)

0.021

0.005

3.3 (1.5 - 7.2)

1R

93 (49)

75 (60)

0.457

0.344

1.6 (0.7 - 3.3)

0R

15 (8)

19 (15)

1

ITGA5-1160

(N = 185)

(N = 124)

 T-carrier

2R: 1R: 0R

44 (24): 115 (62): 26 (14)

10 (8): 67 (54): 47 (38)

<1×10^-4

ITGB1 -1949

 A-carrier

ITGB1 +31804

2R

44 (24)

10 (8)

<1×10^-4

<1×10^-4

8.0 (3.4 - 18.4)

 C-carrier

1R

115 (62)

67 (54)

2×10^-4

3×10^-4

3.1 (1.8 - 5.5)

With or without

0R

26 (14)

47 (38)

1

COX-2 -1195

 G-carrier

IL10 -592 AA

(N = 193)

(N = 135)

IL-10 -592 AA

2R: 1R: 0R

74 (38): 105 (54): 14 (7)

33 (24): 73 (54): 29 (21)

4×10^-4

With or without

ITGA5 -1160

2R

74 (38)

33 (24)

1×10^-4

<1×10^-4

4.6 (2.2 - 9.9)

 T-carrier

1R

105 (54)

73 (54)

6×10^-4

0.003

3.0 (1.5 - 6.0)

0R

14 (7)

29 (21)

1