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Figure 7 | Journal of Biomedical Science

Figure 7

From: Pyrrolidinyl caffeamide against ischemia/reperfusion injury in cardiomyocytes through AMPK/AKT pathways

Figure 7

Effect of PLCA on myocardial I/R induced injury. Cardiac injury was shown after rats subjected to 1 h coronary artery occlusion and followed by 2 h reperfusion. (A) Representative cardiac slices after I/R were shown. (B) Risk size and (C) infarct size were reported. The non-ischemic myocardium stained blue, and the remnants indicated ischemic myocardium. The infarct myocardium stained white, and the non-infarct myocardium stained red. Ratio of red plus white zone to total zone was defined as risk size. Ratio of white zone to red plus white zone was defined as infarct size. (D) Cardiac lactate level was measured. (n = 6) *P < 0.05 vs. control, #P < 0.05 vs. I/R, @ < 0.05 vs. I/R + CA. CA = caffeic acid.

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