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Table 3 Substrate profiles of SHV-128 compared to those of SHV- 2 and SHV-12 enzymes

From: Multidrug-resistant phenotype and isolation of a Novel SHV- beta-Lactamase variant in a clinical isolate of Enterobacter cloacae

 

Relative Vmax

 

SHV-2

SHV-12

SHV-128

Penzylpenicillin

100

100

76

Cephaloridine

123

214

ND

Ceftazidime

<1

16

17

Cefotaxime

27

42

56

Aztreonam

11

110

140