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Table 3 Substrate profiles of SHV-128 compared to those of SHV- 2 and SHV-12 enzymes

From: Multidrug-resistant phenotype and isolation of a Novel SHV- beta-Lactamase variant in a clinical isolate of Enterobacter cloacae

  Relative Vmax
  SHV-2 SHV-12 SHV-128
Penzylpenicillin 100 100 76
Cephaloridine 123 214 ND
Ceftazidime <1 16 17
Cefotaxime 27 42 56
Aztreonam 11 110 140