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Figure 1 | Journal of Biomedical Science

Figure 1

From: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer

Figure 1

Individual gene QPCR analysis showing transcriptional modulations of ATG3, ATG5, ATG7, ATG12, LC3A, LC3B, Belcin1, MyD88, HMGB1, and RAGE in Panc-3.27 and MiaPaCa-2 cells, either mock-irradiated, exposed to FIR (2Gy x 5d) or pretreated with 100 μg/ml of SA-EA, PT-EA, or HT-EA seaweed polyphenol fractions and exposed to FIR. Pretreating the cells with seaweed polyphenols significantly attenuated radiotherapy-induced ATG3, ATG5, ATG7, ATG12, LC3A, LC3B, Belcin1, MyD88, HMGB1, and RAGE transcription in Panc-3.27 and MiaPaCa-2 cells.

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Journal of Biomedical Science

ISSN: 1423-0127