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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family

Fig. 3

Hierarchical clustering of drugs based on similarity of anti-proliferation effect profiles on breast cancer cell lines. Two-dimensional hierarchical clustering was applied to growth inhibitory activity data of 76 anticancer drugs, including midostaurin, of a panel of breast cancer cell lines. The sensitivity level against each drug in a single cell line relative to its mean value across all cell lines was depicted according to the color scale shown at the upper left corner in the figure, and gray indicates missing values. Drugs with similar mechanisms of action tended to cluster together

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