Table 1 Overall diagnostic performance of the SDB DD ICT against reference ELISAs
Dengue Parameter | No. of dengue ELISA pos/neg | No. of SDB DD ICT pos/neg | Sensitivity % (95 % CI) | Specificity % (95 % CI) | PPV % (95 % CI) | NPV % (95 % CI) |
|---|---|---|---|---|---|---|
IgM | 145/194 | 71/187 | 49.3 (41.3-57.4) | 95.9 (92.1-97.9) | 89.9 (81.3-94.8) | 71.9 (66.2-77.0) |
NS1 | 90/249 | 81/247 | 90.0 (82.1-94.7) | 99.2 (97.1-99.8) | 97.6 (91.6-99.3) | 96.5 (93.5-98.1) |
IgG | 256/83 | 100/83 | 39.1 (33.3-45.2) | 100 (95.6-100) | 100 (96.3-100) | 34.7 (29.0-41.0) |
IgM/NS1 | 121/157 | 117/157 | 97.5 (92.9-99.2) | 100 (97.6-100) | 100 (96.8-100) | 98.1 (94.6-99.4) |
IgM/ NS1/ IgG | 181/29 | 179/29 | 98.9 (96.0-99.7) | 100 (88.3-100) | 100 (97.9-100) | 93.6 (79.3-98.2) |