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Table 1 Overall diagnostic performance of the SDB DD ICT against reference ELISAs

From: The performance of the SD BIOLINE Dengue DUO® rapid immunochromatographic test kit for the detection of NS1 antigen, IgM and IgG antibodies during a dengue type 1 epidemic in Jamaica

Dengue Parameter No. of dengue ELISA pos/neg No. of SDB DD ICT pos/neg Sensitivity % (95 % CI) Specificity % (95 % CI) PPV % (95 % CI) NPV % (95 % CI)
IgM 145/194 71/187 49.3 (41.3-57.4) 95.9 (92.1-97.9) 89.9 (81.3-94.8) 71.9 (66.2-77.0)
NS1 90/249 81/247 90.0 (82.1-94.7) 99.2 (97.1-99.8) 97.6 (91.6-99.3) 96.5 (93.5-98.1)
IgG 256/83 100/83 39.1 (33.3-45.2) 100 (95.6-100) 100 (96.3-100) 34.7 (29.0-41.0)
IgM/NS1 121/157 117/157 97.5 (92.9-99.2) 100 (97.6-100) 100 (96.8-100) 98.1 (94.6-99.4)
IgM/ NS1/ IgG 181/29 179/29 98.9 (96.0-99.7) 100 (88.3-100) 100 (97.9-100) 93.6 (79.3-98.2)
  1. 95 % CI is shown in parenthesis. pos = positive; neg = negative; SDB DD = SD BIOLINE Dengue DUO®; ICT = Immunochromatographic test