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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Neurotensin-polyplex-mediated brain-derived neurotrophic factor gene delivery into nigral dopamine neurons prevents nigrostriatal degeneration in a rat model of early Parkinson’s disease

Fig. 1

NTSR1 mRNA and protein expression in the rat substantia nigra at the day of transfection (one week after a unilateral striatal 6-OHDA lesion). a Representative photograph of RT-PCR amplicons showing NTSR1 expression. Actin was used as a control. Lane 1, N1E-115 cells (positive control); lane 2, L929 cells (negative control); lane 3, intact SN (substantia nigra); lane 4, SN with lesion; lane 5, PCR reagents without cDNA (internal control). b Representative confocal micrographs showing TH-immunoreactivity (IR) and NTSR1-IR in the mesencephalon of a hemiparkinsonian rat. The control micrographs correspond to the intact SN contralateral to the side with the lesion

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