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Table 3 Histopathological scoring parameters

From: Alterative effects of an oral alginate extract on experimental rabbit osteoarthritis

Score Description
0 Normal matrix and chondrocytes
1 Uneven cartilage surface with loss of metachromasia around the enlarged cartilage of superficial zone. No fibrillation chondrocyte clusters
2 Some surface erosion, fibrillation and small chondrocyte clusters in superficial zone decreased metachromasia extending to the deep zone
3 Deeper surface erosion with fibrillation extending into the deep zone, large number of chondrocyte clusters containing several cells, major degenerative changes and loss of metachromasia in the cartilage matrix