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Table 2 Seizure behavior of rats injected with 4-AP (10 nmol, n = 6) at different times after 4-AP administration

From: Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus

Convulsive behavior after 4-AP injection

RAT

Minutes

 

15

30

45

60

1

0/1

0/1/2/3

0/1/2/3

0/1/2/3

2

0/1/2/3

0/1/2/3

0/1/2

0/1

3

0/1/2

0/1/2/3

0/1/2/3

0/1/2/3

4

0/1/2

0/1/2/3

0/1/2/3

0/1/2/3

5

0/1

0/1/3

0/1/3

0/1/3

6

0/1/2/3

0/1/2/3/4/5

0/1/2/3/4/5

0/1/2/3

  1. The values represent seizure behavior according to the modified Racine Scale [19]:0, behavioral arrest (motionless), piloerection, excitement and rapid breathing; 1, movement of the mouth, lips, tongue and vibrissae as well as salivation; 2, head and eye clonus; 3, forelimb clonus, “wet dog shakes”; 4, clonic rearing; 5, clonic rearing with a loss of postural control and uncontrolled jumping