All CKD | CKD I-II | CKD III | CKD IV | CKD V | P value | |
---|---|---|---|---|---|---|
N | 240 | 41 | 75 | 58 | 66 | |
Age, year | 61.83 ± 11.61 | 58.84 ± 12.44 | 60.96 ± 10.85 | 62.83 ± 11.41 | 63.82 ± 12.57 | NS |
Male, n (%) | 151 (62.92 %) | 30 (73.17 %) | 54 (72.00 %) | 33 (56.90 %) | 34 (51.52 %) | < 0.01 |
BMI, kg/m2 | 23.68 ± 4.14 | 24.23 ± 4.35 | 24.64 ± 4.16 | 22.34 ± 3.54 | 23.26 ± 4.12 | < 0.01 |
Smoke history, n (%) | 49 (20.42 %) | 6 (14.63 %) | 14 (18.67 %) | 16 (27.59 %) | 13 (19.70 %) | NS |
MABP, mmHg | 100.67 (93.00–110.83) | 95.33 (90.00–104.58) | 96.67 (91.67–108.33) | 103.33 (93.33–113.33) | 103.67 (96.67–115.83) | < 0.05 |
FBG, mmol/L | 5.03 ± 0.84 | 4.81 ± 0.62 | 5.26 ± 0.90 | 4.73 ± 0.75 | 5.15 ± 0.89 | NS |
Hemoglobin, g/dl | 110.45 ± 31.26 | 135.79 ± 28.37 | 126.43 ± 26.54 | 108.58 ± 18.46 | 83.89 ± 18.45 | < 0.01 |
Albumin, g/L | 37.90 (33.25–40.50) | 38.00 (32.10–42.50) | 37.50 (35.00–41.50) | 36.25 (32.50–39.50) | 36.00 (32.05–39.10) | NS |
eGFR, ml/min/1.73m2 | 20.05 (12.43–49.32) | 83.57 (71.28–108.35) | 44.56 (37.72–53.52) | 24.53 (19.35–26.42) | 8.17 (5.84–10.52) | < 0.01 |
Uric acid, mmol/L | 467.51 ± 133.13 | 354.72 ± 114.87 | 445.16 ± 98.76 | 494.32 ± 112.53 | 509.58 ± 157.19 | < 0.01 |
TC, mmol/L | 4.74 (4.11–5.89) | 4.83 (4.17–5.69) | 5.15 (4.13–6.18) | 5.31 (4.27–6.36) | 4.36 (3.65–5.23) | < 0.01 |
TG, mmol/L | 1.69 (1.22–2.52) | 1.75 (1.12–2.59) | 1.84 (1.26–2.87) | 1.78 (1.36–2.51) | 1.52 (1.12–2.16) | < 0.01 |
LDL-C, mmol/L | 3.14 (2.40–3.97) | 3.24 (2.58–4.07) | 3.39 (2.57–4.31) | 3.22 (2.71–4.14) | 2.82 (2.31–3.49) | < 0.01 |
HDL-C, mmol/L | 1.25 (1.02–1.49) | 1.36 (1.13–1.64) | 1.31 (1.00–1.58) | 1.23 (1.12–1.53) | 1.15 (1.03–1.56) | < 0.01 |
Calcium, mmol/L | 2.18 ± 0.28 | 2.22 ± 0.34 | 2.15 ± 0.24 | 2.09 ± 0.31 | 2.14 ± 0.25 | NS |
Phosphate, mmol/L | 1.50 ± 0.42 | 1.29 ± 0.37 | 1.35 ± 0.44 | 1.54 ± 0.50 | 1.71 ± 0.62 | < 0.01 |
hs-CRP, mg/L | 2.24 (1.00–4.10) | 1.80 (1.00–3.50) | 1.84 (1.00–4.87) | 2.36 (1.00–3.56) | 3.64(2.03–5.84) | < 0.01 |
Drug use | ||||||
ACEI, n (%) | 97 (40.42 %) | 30(73.17 %) | 31 (41.33 %) | 23 (39.66 %) | 13 (19.70 %) | < 0.01 |
ARB, n (%) | 81 (33.75 %) | 17 (41.46 %) | 28 (37.33 %) | 19 (32.76 %) | 17 (25.76 %) | NS |
CCB, n (%) | 135 (56.25 %) | 10 (24.39 %) | 38 (50.67 %) | 32 (55.17 %) | 55 (83.33 %) | < 0.01 |
β-blocker, n (%) | 62 (25.83 %) | 7 (17.07 %) | 17 (22.67 %) | 18 (31.03 %) | 20 (30.30 %) | NS |
Statin, n (%) | 47 (19.58 %) | 5 (12.20 %) | 23 (30.67 %) | 11 (18.97 %) | 8 (12.12 %) | < 0.05 |
Phosphate binder, n (%) | 58 (24.17 %) | 0 (0 %) | 7 (9.33 %) | 13 (22.41 %) | 38 (57.58 %) | < 0.01 |
Active VitD, n (%) | 14 (5.83 %) | 0 (0 %) | 0 (0 %) | 3 (5.17 %) | 11 (16.67 %) | < 0.01 |