Fig. 5From: RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cellsThe effect of FA upstream gene knockdowns on proliferation and FANCD2 monoubiquitination in SK-MES-1 cells. a Knockdowns of FANCF, FANCL, or both them inhibited the proliferation rates, and (b, c) reduced FANCD2 monoubiquitination levels after cisplatin treatment. (d) Knockdown of FANCD2, or double knockdown of FANCD2 and FANCF, or and FANCL suppressed the proliferation rate, and (e, f) dropped FANCD2 monoubiquitination levels after cisplatin treatmentBack to article page