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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

Fig. 2

The tail-flick latency was measured every day 30 min after i.p injection of saline or morphine (a). The antinociceptive effect of 10 mg/kg (i.p) morphine on the day 18 in the groups that received saline, vehicle, pioglitazone (40 mg/kg), or GW-9662 (2 mg/kg) for 17 days (b). All date points are expressed as the mean ± SEM. ***: p < 0.001 compared with morphine-vehicle treated animals. : p < 0.05 compared with GW-9662 (2 mg/kg) treated animals. (Sal: Saline; Mor: morphine; Pio: pioglitazone; GW: GW-9662; Veh: vehicle; MPE%: maximal possible effect)

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