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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Involvement of gelsolin in TGF-beta 1 induced epithelial to mesenchymal transition in breast cancer cells

Fig. 6

TGF-β1 induced epigenetic regulation of GSN gene expressions in the CD44+/CD24- subpopulation of MDA-MB231 cells. a Methylation specific PCR (MSPCR) analysis showed epigenetic regulation of GSN gene expression in the CD44+/CD24- subpopulation in MDA-MB-231 cells after TGF-β1 induction. b Real-time quantitative PCR analysis showed decreases of gene expression of two DNA methyltrasferase, DNMT1 and DNMT3B, in the CD44+/CD24- MDA-MB-231 cells subpopulation after TGF-β1 induction. The values are the means ± SEM (n = 6), with * indicating significant difference compared to mock control, and # symbolizing a significant difference compared to post-sort CD44+/CD24- sub-population of MDA-MB231 cells without TGF-β1 treatment

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