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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice

Fig. 4

Aging leads to molecular and cellular senescence of HSCs. a The top panel shows typical senescent cells with blue cytoplasm (arrow) and the bar graph shows the percentage of positive cells quantified by cell counting (bottom panel). b Top panel shows the correlation between intracellular ROS levels and acridine orange fluorescence. The bar graph shows the median fluorescence intensity of acridine orange (bottom panel). c The top panel shows the correlation between the intracellular ROS levels and relative telomere length (RTL). Bottom panel show the percentage of RTL. Values are means ± SEM, *p < 0.05 vs. young

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