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Table 1 Effects of aging on body weight, hematopoietic stem cell number, cell cycle profile and cytokines levels in C57BL/6 J mice
| Parameters | Groups | ||
|---|---|---|---|
| Young | Middle | Aged | |
| Body weight (g) | 28 ± 1 | 29 ± 1 | 34 ± 1* |
| Hematopoietic stem cells (x106) | 1.7 ± 0.2 | 4.3 ± 1 | 5.6 ± 1# |
| Cell cycle (%) | |||
| Sub G0 | 1 ± 0.2 | 4 ± 0.2 | 5 ± 0.5* |
| G0/G1 | 81 ± 2.6 | 75 ± 2.3 | 66 ± 2.9* |
| S/G2/M | 18 ± 2.5 | 21 ± 2.6 | 29 ± 2.8* |
| Myeloid Cytokines (pg/mL) | |||
| IL-6 | 23 ± 2 | 28 ± 2 | 63 ± 8* |
| TNF | 111 ± 7 | 122 ± 7 | 227 ± 27* |
| IL-12p70 | 141 ± 11 | 142 ± 10 | 203 ± 14* |
| Lymphoid Cytokines (pg/mL) | |||
| IFN-γ | 3.2 ± 0.5 | 3.3 ± 0.6 | 4.1 ± 0.3 |
| IL-10 | 181 ± 17 | 164 ± 16 | 149 ± 8 |
