|
Parameters
|
Groups
|
|---|
|
Young
|
Middle
|
Aged
|
|---|
|
Body weight (g)
|
28 ± 1
|
29 ± 1
|
34 ± 1*
|
|
Hematopoietic stem cells (x106)
|
1.7 ± 0.2
|
4.3 ± 1
|
5.6 ± 1#
|
|
Cell cycle (%)
| | | |
|
Sub G0
|
1 ± 0.2
|
4 ± 0.2
|
5 ± 0.5*
|
|
G0/G1
|
81 ± 2.6
|
75 ± 2.3
|
66 ± 2.9*
|
|
S/G2/M
|
18 ± 2.5
|
21 ± 2.6
|
29 ± 2.8*
|
|
Myeloid Cytokines (pg/mL)
| | | |
|
IL-6
|
23 ± 2
|
28 ± 2
|
63 ± 8*
|
|
TNF
|
111 ± 7
|
122 ± 7
|
227 ± 27*
|
|
IL-12p70
|
141 ± 11
|
142 ± 10
|
203 ± 14*
|
|
Lymphoid Cytokines (pg/mL)
| | | |
|
IFN-γ
|
3.2 ± 0.5
|
3.3 ± 0.6
|
4.1 ± 0.3
|
|
IL-10
|
181 ± 17
|
164 ± 16
|
149 ± 8
|
- Values are means ± SEM for six to 11 animals per group. *p < 0.05 vs young and middle age; # p < 0.05 vs young (one-way ANOVA)
