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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Unconserved C terminal of human cytomegalovirus tegument protein pUL76 elicits nuclear aggresome formation and induces DNA damage in transfected cells

Fig. 3

UL76 and its unconserved C terminal induced γ-H2AX foci. HELF cells were transfected with UL76, two deletion mutants or pEGFP-N1 (control vector). Colocalization of γ-H2AX (red) and EGFP fusion proteins (green) were found in nucleus of cells transfected with UL76 (row 2) and unconserved C terminal of UL76 (row 4), but not in cells transfected with pEGFP-N1 (row 1) or pEGFP-UL76N (row 3). Nuclei were counterstained with DAPI (blue)

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