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Table 3 Relationship between PTEN expression and clinicopathological data in CRC patients

From: The prognostic effect of PTEN expression status in colorectal cancer development and evaluation of factors affecting it: miR-21 and promoter methylation

Clinicopathological features N. PTEN protein expression P-value
0 1+ 2+ 3+ PR (%)
Total cases (cancerous) 125 41 34 37 13 67.2  
Age        0.943
  < 50 18 6 4 6 2 66.7  
  ≥ 50 107 35 30 31 11 67.2  
Sex        0.251
 Female 55 15 16 18 6 72.7  
 Male 70 26 18 19 7 62.8  
Tumor size (cm)        0.007
  ≤ 5 79 19 23 27 10 76  
  > 5 46 22 11 10 3 52.2  
TNM Stage        0.011
 I & II 25 3 6 12 4 88  
 III & IV 100 38 28 25 9 62  
Tumor Differentiation        0.534
 High 65 19 17 18 11 70.8  
 Moderate 49 17 14 16 2 65.3  
 Low 11 5 3 3 0 54.5  
PTEN Promoter methylation        0.013
 Methylated 39 18 15 4 2 53.8  
 Unmethylated 86 23 19 33 11 73.2  
  1. PR positive rate, TNM Tumor, Node Metastases staging system