Fig. 3From: Protection against acetaminophen-induced acute liver failure by omentum adipose tissue derived stem cells through the mediation of Nrf2 and cytochrome P450 expressionOmentum-derived ASCs protect the liver against APAP-induced injury via the increased activity of antioxidant enzymes. Liver tissue samples were collected 6 h after omentum-derived ASC transplantation. The lysate was assessed for GSH content and antioxidant enzyme activity. The (a) GSH content and antioxidant enzyme activities of (b) SOD, (c) GPx, and (d) catalase increased significantly after omentum-derived ASC transplantation. The expression of (e) HO-1, (f) Nrf2 and (g) NQO1 are increased significantly 24 h after omentum-derived ASC transplantation. The data are expressed as the means ± SEM, n ≥ 5, *P < 0.05, **P < 0.01Back to article page