Stearoyl-CoA desaturase indexes and n-6/n-3 fatty acids ratio as biomarkers of cardiometabolic risk factors in normal-weight rabbits fed high fat diets

Table 2 Plasma levels of lipids, glucose and body weight values from rabbits fed a control diet (CD), a CD supplemented with 18 % fat (HFD), a high cholesterol diet (HD), a HD supplemented with 18 % fat (HFD-HD)

	CD	HD	HFD	HFD-HD
Body Weight (g)	2138 ± 82	1896 ± 96	2043 ± 46	1845 ± 48
Visceral abdominal fat (g)	0.29 ± 0.05	0.4 ± 0.05	2.07 ± 0.2^a	1.44 ± 0.1^a
Fasting Glucose (mg/dl)	98.5 ± 3.2	108.9 ± 4.7	132.8 ± 8.8^a	148 ± 6^a
Blood pressure (MAP) (mmHg)	62.7 ± 5.1	75.8 ± 2.3	62 ± 7.1	77.4 ± 9
Total Cholesterol (mg/dl)	59.0 ± 6.0	872.3 ± 114^a	64.7 ± 4.8	1793 ± 97^a,b
LDL-cholesterol (mg/dl)	23.8 ± 3.1	666 ± 99^a	27.1 ± 3.4	1391 ± 108^a,b
HDL-cholesterol (mg/dl)	58.8 ± 4.1	164 ± 45^a	29.4 ± 5.7^a	197 ± 38^a
Triglycerides (mg/dl)	92 ± 14	222 ± 33^a	155.6 ± 40^a	253 ± 27^a

Data are expressed as mean ± SE of 8 rabbits. ^a P < 0.05 indicates statistically significant differences between rabbits fed a HFD and HFD-HD with respect to rabbits fed a CD. ^b P < 0.05 indicates statistically significant differences between rabbits fed a HFD-HD and rabbits fed a HD (two way ANOVA and Duncan’s post test)

ISSN: 1423-0127