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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Combination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine

Fig. 1

Legend. Analysis of the cytotoxic activity induced by E7 DNA vaccine plus α-GalCer and MPL combination. CTL activity of the lymphocytes from immunized mice (three mice per group) was measured at 50:1 E/T ratio by LDH release assay kit as described in Material and Methods section. Specific lysis of target cells are shown with nonspecific background lysis subtracted. LDH release was expressed as percent cytotoxicity ± S.D. *** Indicates statistically significant difference between E7 DNA vaccine in combination with α-GalCer and MPL group as determined by one-way ANOVA (P < 0.001) with other groups. ** shows the statistical significant differences between E7 DNA vaccine plus α-GalCer and E7 DNA vaccine plus MPL treatments than the E7 DNA vaccine alone group (P < 0.01). # shows the statistical significant differences between E7 DNA vaccine plus α-GalCer treatment than the E7 DNA vaccine plus MPL group (P < 0.05)

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Journal of Biomedical Science

ISSN: 1423-0127