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Table 1 The influence of M3BIM on activated partial thromboplastin time and prothrombin time in mice

From: Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

 

PBS

0.5 % DMSO

M3BIM

 

30 min

30 min

30 min

60 min

APTT (s)

40.4 ± 2.7

38.2 ± 4.3

39.9 ± 2.1

38.9 ± 1.5

PT (s)

13.1 ± 0.4

13.0 ± 0.4

11.8 ± 0.3

12.4 ± 0.1

  1. M3BIM (24 mg/kg), solvent control (0.5 % DMSO), or a phosphate-buffered saline (PBS) was injected (i.p.) in mice for 30 or 60 min. The platelet-poor plasma was obtained for assay the activated partial thromboplastin time (APTT) and prothrombin time (PT). Data are presented as the means ± SEM (n = 8)
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Journal of Biomedical Science

ISSN: 1423-0127