Fig. 6
a In host rat tissue harvests at 8 weeks post-transplantation, there was positive staining with a human-specific anti-tyrosine hydroxylase (Red) antibody utilized as a human-specific and dopaminergic cell-specific marker. b Grafted cell and host vascular congruency were clearly observed after CD31 (Green) staining, which was both rat-specific and an endothelial cell specific marker. c At 8 weeks post-transplantation, amphetamine induced ipslateral rotation in the treatment group was significantly reduced, as compared to the control sham-transplanted group. d There was a significant reduction in apomorphine induced contra-lateral rotations compared to the control at 8 weeks post-transplantation. e Animals were studied with rota rod and a significant increase in latency to fall was observed in groups of transplanted animals compared to the sham-transplanted controls. Scale bars: A, 200 μm. B, 100 μm