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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Drosophila mitochondrial topoisomerase III alpha affects the aging process via maintenance of mitochondrial function and genome integrity

Fig. 3

Mitochondrial Top3α depletion causes mobility defects in Drosophila. a Mobility of M1L adults decreases rapidly with age as shown by climbing assay. Each experiment included 300 adults of each genotype at the indicated age. One-way ANOVA with Tukey’s multiple test was performed to compare M1L with WT (wildtype) and rescued flies (***P < 0.001). b The muscle of Lawrence (MOL) from wildtype, rescued, and M1L adult males was dissected and stained with anti-HRP (neuron, magenta) and anti-Brp (active zone, cyan) antibodies. c The numbers of active zones (AZ) per bouton (n = 42) were similar for all samples examined in this study

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