Fig. 4From: The genetics and screening of familial hypercholesterolaemia PCSK9 gene. a. Location of the PCSK9 gene on the short (p) arm of chromosome 1 at position 32.3. b. The numbered vertical bars represent exons. c. There are 163 mutations seen in the PCSK9 gene, some causing gain-of–function and some causing loss-of-function. Data extracted from [23–25]Back to article page