Fig. 3

Morphology of fully developed (5-week) MDA-MB 231 xenograft with necrotic core and neovascular blood vessel on the surface or within the mass. There were newly-formed blood vessels on the surface of the developed xenografts identified in situ (a) and from the harvested tissue (b) and inside the tumor mass with histological H&E staining indicated by black arrow heads (d), which was magnified from the green lines marked region in (c). The cells with mitotic figures are indicated by black arrows in (d)