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Table 1 Occurrence of contrast features from the model for malignancy prediction

From: Characterization of a murine xenograft model for contrast agent development in breast lesion malignancy assessment

Contrast features (Method)   Xenograft types Occurrence (frequency %)
   Malignant Benign
   MDA-MB 231 MCF-7  
Molecular targeting contrast CD31 (IHC) 5/5 (100 %) 6/6 (100 %) 0/11 (0 %)
  VEGF (IHC) 5/5 (100 %) 6/6 (100 %) 0/11 (0 %)
Non-targeting contrast Rim enhancement (DCE-MDCT) 11/11 (100 %) 11/12 (100 %) 2/23 (8.7 %)
  Time-density curve    
Washout T1/2 < 100 min (DCE-MDCT) 10/11 (90.9 %) 10/12 (83.3 %) 0/23 (0 %)
Endogenous contrast Angular/ill-defined margin (grey scale US) 9/10 (90 %) 14/17 (82.4 %) 0/27 (0 %)
  Angular/ill-defined margin (DCE-MDCT) 10/11 (90.9 %) 9/12 (75 %) 1/23 (4.3 %)
  Orientation    
width/height > 2.2 (grey scale US) 10/10 (100 %) 17/17 (100 %) 0/27 (0 %)
  Neovascular flow (color Doppler US) 1/10 (10 %) 3/17 (17.6 %) 0/27 (0 %)
  1. Occurrence = occurred number of specific type xenograft/total number of specific type xenograft; frequency % = occurred number of specific type xenograft/total number of specific type xenograft × 100 %