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Table 1 Cardiac function measurements on WT and RCM TG mice

From: Green tea extract catechin improves internal cardiac muscle relaxation in RCM mice

 

WT control

WT EGCg

RCM control

RCM EGCg

Parameters

 Body weight (g)

31.67 ± 1.53

30.67 ± 1.61

27.25 ± 1.21*

28.35 ± 1.28*

 Heart rate (bpm)

470.72 ± 38.12

481.37 ± 44.15

450.75 ± 50.76

460.17 ± 49.73

Atria

 LAEDD (mm)

2.12 ± 0.02

2.13 ± 0.03

2.29 ± 0.04**

2.21 ± 0.05*‡

 LAESD (mm)

1.67 ± 0.03

1.69 ± 0.04

1.74 ± 0.06

1.71 ± 0.05

 RAEDD (mm)

2.11 ± 0.05

2.12 ± 0.06

2.31 ± 0.11**

2.26 ± 0.05*

 RAESD (mm)

1.71 ± 0.06

1.69 ± 0.03

1.64 ± 0.04

1.68 ± 0.05

LV end diastole

 IVS (mm)

0.75 ± 0.04

0.76 ± 0.03

0.75 ± 0.04

0.74 ± 0.03

 LVEDD (mm)

3.88 ± 0.07

3.85 ± 0.04

3.42 ± 0.0 6*

3.62 ± 0.03*‡

 LV PW (mm)

0.76 ± 0.02

0.75 ± 0.04

0.76 ± 0.03

0.73 ± 0.03

 LV Volume (μl)

64.67 ± 1.71

63.95 ± 2.16

46.16 ± 2.24**

55.92 ± 1.19*‡

LV end systole

 IVS (mm)

1.27 ± 0.03

1.27 ± 0.04

1.24 ± 0.02

1.25 ± 0.03

 LVESD (mm)

2.05 ± 0.05

2.08 ± 0.06

1.58 ± 0.02**

1.75 ± 0.03*‡

 LV PW (mm)

1.22 ± 0.03

1.22 ± 0.04

1.21 ± 0.03

1.21 ± 0.02

 LV Volume (μl)

13.03 ± 0.43

13.42 ± 0.61

5.96 ± 0.71

9.35 ± 0.80**ǂǂ

 Ejection Fraction (%)

79.85 ± 1.41

79.01 ± 1.00

80.33 ± 1.91

80.57 ± 2.16

 Fractional Shortening (%)

46.72 ± 1.22

45.38 ± 0.66

47.95 ± 1.84

47.44 ± 2.33

Mitral Doppler

 E (mm/s)

827.61 ± 22.05

829.75 ± 24.22

740.81 ± 18.93*

809.04 ± 25.14

 A (mm/s)

657.95 ± 12.34

667.35 ± 16.48

560.33 ± 33.66 *

633.57 ± 26.83

 E/A

1.26 ± 0.04

1.24 ± 0.02

1.32 ± 0.05

1.27 ± 0.05

 IVRT (ms)

16.41 ± 0.44

16.44 ± 0.46

21.43 ± 0.54**

18.53 ± 0.51*‡

 IVCT (ms)

10.58 ± 0.33

11.05 ± 0.29

10.36 ± 0.75

10.86 ± 0.53

  1. Values are expressed as means ± SE for each group. LA left atrium, RA right atrium, LV left ventricle, EDD end diastolic dimension, ESD end systolic dimension, PW posterior wall thickness of LV, IVS intra-ventricular septum, EF ejection fraction of LV, FS fractional shortening of LV, E mitral Doppler E peak velocity, A mitral Doppler A peak velocity, IVRT isovolumetric relaxation time, IVCT isovolumetric contraction time. Statistical significance was determined by ANOVA followed by post hoc Newman-Keuls (SNK) tests
  2. *p <0.05 compared to WT control, **p <0.01 compared to WT control; Ç‚p <0.05 compared to RCM control; Ç‚Ç‚p <0.01 compared to RCM control