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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Effects of exogenous nicotinamide adenine dinucleotide (NAD+) in the rat heart are mediated by P2 purine receptors

Fig. 3

NAD + −induced AP shortening in the presence of selective antagonists of P1 and P2-purinoreceptors in LA preparations. a, b relative APD90 in the presence of P1 blocker DPCPX (0.1 μM, panel a) or P2 blocker suramine (sur, 10 μM, panel b), 10 μM NAD+ without blockers or NAD+ applied after DPCPX or suramine. APD90 is expressed in % of control APD90. NS – no significant difference, Mann–Whitney test. * - significant difference, Mann–Whitney test, p < 0.05. c, d representative traces of APs before and during NAD+ application in the presence of 0.1 μM DPCPX c or 10 μM suramine d

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