Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway

Table 1 Phenotype frequencies of ISV defects in embryos at 48 hpf^a

Injection	Normal ISV (%)	Aberrant ISV (%)	Notch1-induced deformity (%)	Total live embryos (experiment repeats)
5msMO1
2 ng	67 ± 14	33 ± 15	0 ± 0	230 (3)
MO1
2 ng	25 ± 1	75 ± 2	0 ± 0	217 (3)
MO1/Notch1
2 ng/12.5 pg	36 ± 1	59 ± 4	5 ± 3	312 (3)

Mean ± SEM was estimated from experimental replicates
ISV intersegmental vessel, MO morpholino, hpf hour post fertilization
^aFrequency was calculated as the number of embryos with the indicated phenotype divided by the number of live embryos in each experiment

ISSN: 1423-0127