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Table 5 Comparison of liver and kidney function of patients before, during, and after DC vaccination

From: A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment

Patient Liver function Kidney function
GOT/GPT Bilirubin Creatinine
Day 0 (before) Day 36 (during) Day 57 (after) Day 0 (before) Day 36 (during) Day 57 (after) Day 0 (before) Day 36 (during) Day 57 (after)
1 26/40 40/33 47/37 0.89 1.04 1.35 1.0 1.1 1.0
2 47/38 offa off 1.15 off off 0.8 off off
3 19/14 27/26 54/84 1.0 0.68 0.65 0.8 0.7 0.7
4 38/19 94/37 off 0.95 1.01 off 0.7 0.8 off
5 20/23 17/17 20/39 0.7 1.1 0.5 1.1 1.2 1.0
6 22/9 26/11 22/13 0.9 0.8 1.0 1.2 2.2 2.3
7 24/39 52/55 47/46 0.4 1.2 1.0 1.0 0.9 0.8
8 50/41 132/61 off 1.4 35.5 off 0.8 0.8 off
9 39/15 29/14 41/28 0.4 0.4 0.3 0.5 0.5 0.4
10 32/17 53/30 49/48 0.9 0.8 0.9 0.9 0.8 0.7
11 19/12 20/11 23/14 0.53 0.3 0.33 0.9 0.8 0.8
12 25/24 41/45 28/30 1.5 2.25 1.53 0.9 1.0 1.0
  1. a“off” indicates samples not available for analysis because of withdrawal or termination of enrolled patients from this study