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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-γ2

Fig. 1

Nova1 promotes tumor growth in vivo and the expression of GABAARγ2 in tumor tissue is restro-regulated by Nova1. Photography of in vivo tumorigeniticity of Huh7-shNova1 (a) and SMMC7721-Nova1 (b). c Growth kinetics of tumor volumn in nude mice. Tumor diameters were measured every 7 days. d Representative photographs of immunohistochemical analysis of GABAARγ2 and GABA antigens in tumors of nude mice (original magnification:×200; upper right coner,×400). e Western blot of the expression of GABAARγ2 and GABA in tumors of nude mice under the regulation by overexpression or down-regulation the expression of Nova1

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