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Table 2 Univariate analyses of factors associated with survival and recurrence

From: RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-γ2

Variables

OS

DFS

Hazard ratio (95 % CI)

P

Hazard ratio (95 % CI)

P

Sex(male vs female)

1.126 (0.525–2.416)

0.76

1.483 (0.844–2.608)

0.171

Age,y(≥53 vs. < 53)

1.609 (0.902–2.874)

0.107

0.802 (0.361–1.781)

0.588

Preoperative AFP, ng/ml (>20 vs. ≤ 20)

1.320 (0.721–2.415)

0.369

1.390 (0.778–2.485)

0.266

HBsAg (negative vs.positive)

1.175 (0.598–2.311)

0.639

1.040 (0.563–1.925)

0.899

Liver cirrhosis (yes vs. no)

3.303 (1.290–8.455)

0.013

2.878 (1.121–7.385)

0.028

Vascular invasion (yes vs. no)

1.976 (1.004–3.891)

0.049

0.922 (0.523–1.625)

0.78

Tumor size, cm (>5 vs. ≤ 5)

1.107 (0.609–2.014)

0.738

0.818 (0.468–1.429)

0.48

Tumor number (multiple vs.single)

1.718 (0.886–3.330)

0.109

1.265 (0.646–2.475)

0.493

Tumor differentiation (I-II vs.III-IV)

1.215 (0.566–2.608)

0.618

0.971 (0.472–1.999)

0.937

TNM stage (III vs.I-II)

2.253 (1.209–4.199)

0.011

2.137 (1.177–3.880)

0.013

BCLC stage (C vs. A/B)

1.976 (1.004–3.891)

0.049

0.922 (0.523–1.625)

0.78

Intratumoral GABAARγ2 (high vs.low)

0.372 (0.203–0.683)

0.001

0.419 (0.232–0.755)

0.004

Peritumoral GABAARγ2 (high vs.low)

1.302 (0.719–2.355)

0.384

1.503 (0.850–2.657)

0.161