Table 3 Multivariate analyses of factors associated with OS and DFS

 Liver cirrhosis (yes vs. no)

3.711 (1.448–9.510)

0.006

 Vascular invasion (yes vs.no)

NS

 TNM stage (II-III vs. I)

NS

 BCLC stage (B/C vs. A)

2.591 (1.251–5.365)

0.01

 Intratumoral GABAARγ2 (high vs.low)

0.309 (0.163–0.588)

<0.001

 Liver cirrhosis (no vs.yes)

3.334 (1.386–8.020)

0.007

 TNM stage (II-III vs. I)

2.009 (1.050–3.844)

0.035

 Intratumoral GABAARγ2 (high vs.low)

0.351 (0.183–0.647)

0.002