Fig. 1

Clinical application of human mesenchymal stem cells (MSCs) for immune- and inflammation-mediated diseases. Graph is a summary of the number of clinical trials using MSC therapy in immune-/inflammation-mediated diseases, as registered on the website https://clinicaltrials.gov/ (accessed April 2016). MS, multiple sclerosis; T1DM, type 1 diabetes mellitus; GVHD, graft versus host disease; OA, osteoarthritis; IBD, inflammatory bowel disease