TY - JOUR AU - Yang, Andrew AU - Farmer, Emily AU - Wu, T. C. AU - Hung, Chien-Fu PY - 2016 DA - 2016/11/04 TI - Perspectives for therapeutic HPV vaccine development JO - Journal of Biomedical Science SP - 75 VL - 23 IS - 1 AB - Human papillomavirus (HPV) infections and associated diseases remain a serious burden worldwide. It is now clear that HPV serves as the etiological factor and biologic carcinogen for HPV-associated lesions and cancers. Although preventative HPV vaccines are available, these vaccines do not induce strong therapeutic effects against established HPV infections and lesions. These concerns create a critical need for the development of therapeutic strategies, such as vaccines, to treat these existing infections and diseases. SN - 1423-0127 UR - https://doi.org/10.1186/s12929-016-0293-9 DO - 10.1186/s12929-016-0293-9 ID - Yang2016 ER -