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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

Fig. 5

Contrast-to-noise ratio (CNR). Panel a Representative ΔR2* maps of 0.5 mm brain slices from the cerebellum (upper left slice) in percent increase from baseline (color scale was 0–250%) from one mouse (no amphetamine, SPION-miD2861). ΔR2* Maps [(Post R2*−bR2*)/bR2*) ×100%]. Panel b ROI (arrows) of the somatosensory cortex (SSC, contralateral to icv port) for data analysis [18, 20]. Panel c Elevations of ΔR2* values of the SSC by longitudinal MRI in vivo; mean ΔR2* values of four mice are shown. Contrast-to-noise ratio was calculated for R2* data at 2, 4, and 6 h. CNR = (R2* of mean/[SD of baseline]1/2)

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