Skip to main content
Fig. 9 | Journal of Biomedical Science

Fig. 9

From: Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

Fig. 9

Quantitative HDAC5 expression using SPION-mid2861, MCE MRI, RT-PCR and immunohistochemistry. Panel a Chronic versus Control. There was a general reduction in HDAC5 mRNA measured using SPION-miD2861. The p values are listed above each ROI. Panel b The copy number of HDAC5 mRNA on the 212 region was measured from total striatal RNA of S1 (SS), A1 (A1s) and A7Wa (A8s) paradigms (n = 4 each) using TaqMan® analysis. Panel c & d HDAC5 protein (red) shows antigen around the nuclei (purple, DAPI) in the striatum; the intensity of total HDAC5 protein was similar in both S1 and A1 paradigms but it was null in the chronic (A7WA) paradigm

Back to article page