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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: miR-199a-3p inhibits cell proliferation and induces apoptosis by targeting YAP1, suppressing Jagged1-Notch signaling in human hepatocellular carcinoma

Fig. 2

Overexpression of miR-199a-3p and knockdown of YAP1 inhibit proliferation and induce apoptosis in HCC cells. a and d The effects of overexpression of miR-199a-3p and knockdown of YAP1 on Huh7 cell proliferation are detected by MTT assay. b and e The effects of overexpression of miR-199a-3p and knockdown of YAP1 on Huh7 cell apoptosis are assessed by flow cytometry assay. c and f Caspase 3/7 activity is measured in Huh7 cells transfected with miR-control, miR-199a-3p mimic, si-control or si-YAP1. *P < 0.05, **P < 0.01 and ***P < 0.001

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Journal of Biomedical Science

ISSN: 1423-0127