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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: miR-199a-3p inhibits cell proliferation and induces apoptosis by targeting YAP1, suppressing Jagged1-Notch signaling in human hepatocellular carcinoma

Fig. 5

miR-199a-3p and YAP1 regulated proliferation and apoptosis of HCC cells through Jagged1-Notch signaling. a and b Huh7 cells transfected with miR-199a-3p mimics and si-YAP1 show signigficantly lower protein levels of NICD and Hes-1 than control cells. ce Huh7 cells treated by miR-199a-3p mimic and DAPT have an obviously lower cell proliferation rate and a significantly higher apoptosis rate than the cells treated by miR-control and DAPT. *P < 0.05 and **P < 0.01

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