Fig. 2
From: Developing precision medicine for people of East Asian descent
The influence of genetics and lifestyle choices on esophageal cancer risk. People with the ALDH2*2 variant who consume alcohol and are also fast metabolizers of alcohol by having the ADH1B variant have an increased risk for developing esophageal cancer. If the person also smokes cigarettes, the risk of developing esophageal cancer is potentially 189 times higher