Table 1 List of genes linked to NCL in humans
Protein | Disease |
|---|---|
PPT1/CLN1 | Infantile NCL |
TPP1/CLN2 | Late-infantile NCL |
CLN3 | Juvenile NCL |
DNAJC5/CLN4 | Adult-onset NCL, Kufs disease, Parry disease |
CLN5 | Late-infantile NCL (Finnish variant) |
CLN6 | Variant late-infantile NCL |
MFSD8/CLN7 | Late-infantile NCL (Turkish variant) |
CLN8 | Northern epilepsy (epilespy, progressive with mental retardation, EPMR) |
CTSD/CLN10 | Congenital, neonatal and late infantile NCL |
PGRN/CLN11 | Adult-onset NCL, frontotemporal dementia in heterozygotes |
ATP13A2/CLN12 | Juvenile-onset NCL |
CTSF/CLN13 | Adult-onset NCL |
KCTD7/CLN14 | Infantile NCL |