rs1229984 (Dysfunctional Allele = G) | G/G | A/G | A/A | P |
---|---|---|---|---|
No. of patients | 12 | 80 | 90 | |
Clinical Characteristics | ||||
 Age (year) | 61 ± 11 | 61 ± 10 | 61 ± 11 | 0.959 |
 Age of onset (year) | 58 ± 11 | 56 ± 12 | 57 ± 11 | 0.780 |
 Male gender | 10 (83.3%) | 66 (82.5%) | 79 (87.8%) | 0.827 |
 BMI (kg/m2) | 23.7 ± 2.7 | 24.3 ± 3.3 | 23.9 ± 3.4 | 0.775 |
 PAF | 8 (66.7%) | 45 (56.3%) | 55 (61.1%) | 0.857 |
 Diabetes mellitus | 0 (0%) | 16 (20.0%) | 15 (16.7%) | 0.091 |
 Ischemic heart disease | 0 (0%) | 1 (1.2%) | 0 (0%) | 0.898 |
 AHI/hour | 19.1 ± 11.9 | 15.7 ± 15.0 | 18.8 ± 14.5 | 0.389 |
 Alcohol intake (ethanol g/day) | 45.1 ± 33.5 | 27.8 ± 27.6 | 22.7 ± 24.3 | 0.057 |
Echocardiographic Findings | ||||
 LAD(mm) | 34.2 ± 10.8 | 37.1 ± 6.4 | 37.4 ± 5.5 | 0.262 |
 LA volume index (ml/m2) | 37.8 ± 6.1 | 37.8 ± 11.7 | 39.4 ± 9.6 | 0.346 |
 IVSTd (mm) | 0.90 ± 0.12 | 0.83 ± 0.14 | 0.89 ± 0.14 | 0.134 |
 LVDd (mm) | 51.7 ± 4.8 | 46.9 ± 3.9 | 48.5 ± 5.4 | 0.525 |
 EF(%) | 61.6 ± 5.8 | 59.3 ± 5.7 | 58.0 ± 7.6 | 0.109 |
EPS parameters | ||||
 AA (mm) | 861.3 ± 207.3 | 829.2 ± 152.8 | 831.3 ± 147.8 | 0.600 |
 AH (ms) | 114.5 ± 9.2 | 91.7 ± 3.1 | 93.1 ± 2.3 | 0.316 |
 HV (ms) | 45.6 ± 9.5 | 39.6 ± 8.5 | 40.5 ± 8.8 | 0.693 |
 AVN ERP (ms) | 289 ± 64 | 151 ± 24 | 155 ± 28 | 0.117 |
 A ERP (ms) | 290.0 ± 40.0 | 238 ± 38.9 | 234 ± 29.8 | 0.0453* |
 SNRT (ms) | 1553.2 ± 622.6 | 1382.2 ± 448.6 | 1390.9 ± 326.1 | 0.643 |