Fig. 1
From: PPARs modulate cardiac metabolism and mitochondrial function in diabetes
Peroxisome proliferator-activated receptor (PPAR)-α regulates fatty acid utilization and β-oxidation in cardiac metabolism. Stars indicate transporters and enzymes involved in fatty acid metabolism which are regulated by PPAR-α. FATP, fatty acid transport protein; FABP, fatty acid binding protein; ACS, acyl-CoA synthetase; CPT-I, carnitine palmitoyltransferase-I; CPT-II, carnitine palmitoyltransferase II; TCA, tricarboxylic acid; GLUT4, glucose transporter four; MPC, mitochondrial pyruvate carrier; and PDH, pyruvate dehydrogenase. Modified from [8]