Fig. 3
From: Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials
Effects of sarcosine or DMG on glutamate/glycine-evoked excitatory field potentials. The experimental protocol (a), the representative field potential recordings (b), and the frequency and amplitude of NMDA receptor-mediated excitatory field potentials (c) after application of glutamate, glycine, glutamate (100 μM) plus glycine (10 μM) and various concentrations (10, 30 and 100 μM) of sarcosine and DMG sequentially with glutamate plus glycine. The data were analyzed by one-way repeated measures ANOVA (Frequency: F9,27 = 50.58, p < 0.001; Amplitude: F9,27 = 54.64, p < 0.001). Data are expressed as percentage of baseline, mean ± SEM (n = 4). ***p < 0.001 compared with baseline. ###p < 0.001 compared with glutamate plus glycine