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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials

Fig. 4

Effects of D-cycloserine on NMDA receptor-mediated excitatory field potentials. The experimental protocol (a), the representative field potential recordings (b), and the frequency and amplitude of NMDA receptor-mediated excitatory field potentials (c) after the application D-cycloserine alone, co-application of D-cycloserine (10 and 30 μM) with glutamate or glutamate plus glycine. The data were analyzed by one-way repeated measures ANOVA (Frequency: F8,24 = 70.25, p < 0.001; Amplitude: F8,24 = 100.8, p < 0.001). Data are expressed as percentage of baseline, mean ± SEM (n = 4). ***p < 0.001 compared with baseline. ###p < 0.001 compared with glutamate plus glycine. DCS:D-cycloserine

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