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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation

Fig. 1

Localization of JAB1 in CD68+ MΦ in atherosclerotic plaques of hypercholesterolemic ApoE−/− mice. Representative cross-sections of the brachiocephalic trunk of ApoE−/− mice at 30 weeks of age are shown. In an atherosclerotic plaque of ApoE−/− mice JAB1-immunoreactivity (a, b) was localized in CD68+ MΦ (c, d), as seen in merge (e, f) labelled by *. JAB1- and CD68-immunoreactivity was detected by confocal laser scanning microscopy (Nikon Eclipse) and analyzed with Fiji ImageJ software. Nuclei were counterstained with DAPI (blue). Representative photos from 4 independent experiments are shown. Bars: 50 μm

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