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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation

Fig. 4

TC, FC and CE contents in non-transfected, siJAB1- or nsiJAB1- U937 MФ. Cells (1*106 cells/well) were cultured in the presence of PMA (20nM) for 24 h and transfected with siRNA JAB1 (siJAB1-MФ) or negative siRNA (nsiJAB1-MФ) for 48 h. Non-transfected MФ, nsiJAB1-MФ or siJAB1- MФ were incubated (4 h) with oxLDL (50 μg/ml) or without (control). a TC, total cholesterol, (b) FC, free cholesterol and (c) EC, esterified cholesterol, were normalized to total protein. Data are expressed as mean + SEM of 4 independent experiments. *p < 0.05 significance vs. corresponding control

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